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Association Between Menopause and Voice.

Sidika Deniz Yalım1, Selcuk Bayram2, Nuray Bayar Muluk3

  • 1Department of Otorhinolaryngology, Adana City Training & Research Hospital, Ministry of Health, Turkey.

Ear, Nose, & Throat Journal
|November 17, 2025
PubMed
Summary
This summary is machine-generated.

Menopause impacts voice quality, leading to lower frequency and perceptually reduced grade, roughness, and strain in postmenopausal women compared to premenopausal women. These vocal changes, however, do not significantly affect their quality of life.

Keywords:
acousticslarynxmenopausevoicevoice quality

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Area of Science:

  • Otolaryngology
  • Women's Health
  • Acoustic Analysis

Background:

  • Menopause is associated with various physiological changes.
  • The effects of menopause on voice quality are not fully understood.
  • Hormone therapy (HT) is a common intervention for menopausal symptoms, but its impact on voice requires further clarification.

Purpose of the Study:

  • To evaluate and clarify the effects of menopause on voice.
  • To compare voice parameters between postmenopausal women not receiving HT and premenopausal women.

Main Methods:

  • Acoustic voice analysis of 50 postmenopausal women (no HT) and 50 premenopausal women.
  • Measured fundamental frequency (F0), jitter, shimmer, harmonic-to-noise ratio (HNR), and noise-to-harmonic ratio (NHR).
  • Perceptual assessment using the Grade, Roughness, Breathiness, Asthenia, Strain (GRBAS) scale and self-evaluation via the Voice Handicap Index-10 (VHI-10).

Main Results:

  • Postmenopausal women exhibited lower F0, Grade (G), Roughness (R), and Strain (S) scores.
  • Age correlated significantly with G, R, A (Asthenia), S, and F0.
  • No significant differences were found in VHI-10, jitter, shimmer, HNR, or NHR between the groups.

Conclusions:

  • Postmenopausal women, compared to premenopausal women, have voices with lower frequency and perceptually lower grade, roughness, and strain.
  • These voice changes associated with menopause do not appear to negatively impact self-perceived quality of life.
  • Further research may explore the long-term vocal effects and potential interventions.