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Association between erythrocyte folate and pregnancy: A scientometric analysis
Yu Xia1, Xuanyi Wang2, Datong Liu3
1Yu Xia, Department of Obstetrics, Rizhao People's Hospital, Rizhao, Shandong Province 276899, P.R. China.
Pakistan Journal of Medical Sciences
|November 17, 2025
Summary
Erythrocyte folic acid levels are linked to pregnancy outcomes. Future research should focus on risk factors and prevention strategies for maternal and infant health.
Area of Science:
- Obstetrics and Gynecology
- Nutritional Science
- Public Health
Background:
- The association between erythrocyte folic acid and pregnancy is a critical area of research.
- Understanding trends in this field is essential for public health initiatives.
Purpose of the Study:
- To conduct a scientometric analysis of research trends on erythrocyte folic acid and pregnancy.
- To identify key authors, institutions, countries, and research areas.
Main Methods:
- A comprehensive literature search was conducted on the Web of Science database (1980-2023).
- CiteSpace and VOSviewer software were employed for visual network analysis of keywords, countries, authors, and institutions.
Main Results:
- Analysis of 243 studies revealed key research areas including the impact of folate, Vitamin B12, and homocysteine on pregnant women and infants.
- The United States and the UK are leading research nations.
- Research highlights the role of folic acid in preventing neural tube defects (NTDs) and reducing maternal/infant complications.
Conclusions:
- Erythrocyte folate is significantly associated with pregnancy.
- Future research should prioritize identifying risk factors and prevention strategies.
- Optimal folic acid intake (0.4mg/day) is crucial for NTD prevention, necessitating improved dietary guidance for pregnant women.
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