Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classification of Illness01:17

Classification of Illness

9.4K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
9.4K
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

1.0K
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
1.0K
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

887
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
887
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

45
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
45
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

29
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
29
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

36
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
36

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Conjugates of Heme and Intrinsically Disordered Peptides toward the Development of Synthetic Artificial Oxygen Carriers.

Bioconjugate chemistry·2026
Same author

Severe Hypokalemia and Life-Threatening Ventricular Arrhythmias: A Case of Normotensive Primary Aldosteronism.

Cureus·2026
Same author

A Contemporary Comparison of Modern Cementless to Cemented Femoral Stems for Treatment of Femoral Neck Fractures.

The Journal of arthroplasty·2026
Same author

Subclinical neuropsychiatric trait variation in parents of children with autism spectrum disorder: a cohort study.

Molecular autism·2026
Same author

Parkinson's disease increases readmission, non-routine discharge, and length of stay following primary cervical fusion.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

Nationwide Comparison of 2 year Revision Surgery Risk After Hybrid Cervical Surgery with 2-Level ACDF and 2-Level CDR Surgical Technique.

Global spine journal·2026
Same journal

L5 Is a Reliable Lower Instrumented Vertebra in Selected Adult Spinal Deformity Patients.

Global spine journal·2026
Same journal

Full-Endoscopic Posterior Cervical Decompression Versus Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis.

Global spine journal·2026
Same journal

Impact of Culture Status on Outcomes in Vertebral Osteomyelitis: A Retrospective Cohort Study of 206 Patients.

Global spine journal·2026
Same journal

A High Frailty Burden is a Strong Predictor of Adverse Postoperative Outcomes in Geriatric Lumbar Spine Surgery: A Retrospective Cohort Study.

Global spine journal·2026
Same journal

Perioperative Complications of Oblique Lateral Interbody Fusion With Unilateral Pedicle Screw Fixation in a Single Lateral Position: A Retrospective Case Series.

Global spine journal·2026
Same journal

A Global Survey on Intra-operative Neuromonitoring (IONM) Practices, Attitudes Towards Its Use, and Barriers Among Spine Surgeons.

Global spine journal·2026
See all related articles

Related Experiment Video

Updated: May 7, 2026

Evaluation of Patients' Posture and Gait Profile After Lumbar Fusion Surgery by Video Rasterstereography and Treadmill Gait Analysis
07:44

Evaluation of Patients' Posture and Gait Profile After Lumbar Fusion Surgery by Video Rasterstereography and Treadmill Gait Analysis

Published on: March 23, 2019

18.8K

New-Onset Psychiatric Disorders After Lumbar Fusion: Predictors, Timing, and Risk Stratification.

Alexander M Ballatori1, Shane Shahrestani2, Andy Ton3

  • 1Department of Orthopaedic Surgery, University of Southern California, Los Angeles, CA, USA.

Global Spine Journal
|November 17, 2025
PubMed
Summary
This summary is machine-generated.

New psychiatric disorders like depression and anxiety are common after lumbar fusion surgery, often appearing within 90 days. Perioperative opioid use and socioeconomic factors increase this risk, highlighting the need for early mental health screening.

Keywords:
lumbar fusionopioidspsychiatric complicationsrisk stratification

More Related Videos

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
05:30

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

Published on: February 14, 2025

1.5K
Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

1.1K

Related Experiment Videos

Last Updated: May 7, 2026

Evaluation of Patients' Posture and Gait Profile After Lumbar Fusion Surgery by Video Rasterstereography and Treadmill Gait Analysis
07:44

Evaluation of Patients' Posture and Gait Profile After Lumbar Fusion Surgery by Video Rasterstereography and Treadmill Gait Analysis

Published on: March 23, 2019

18.8K
Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
05:30

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

Published on: February 14, 2025

1.5K
Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

1.1K

Area of Science:

  • Neurosurgery
  • Psychiatry
  • Health Services Research

Background:

  • Lumbar fusion surgery is a common procedure for spinal conditions.
  • Postoperative complications can significantly impact patient recovery and quality of life.

Purpose of the Study:

  • To determine the incidence, timing, and predictors of new-onset psychiatric disorders after lumbar fusion.
  • To develop a risk stratification model for early identification of at-risk patients.

Main Methods:

  • Retrospective cohort study using the Nationwide Readmissions Database (2016-2019).
  • Inclusion of adult patients undergoing elective inpatient lumbar fusion, excluding those with prior psychiatric diagnoses.
  • Analysis of new-onset depression, anxiety, suicidal ideation, and homicidal ideation within 12 months post-surgery.

Main Results:

  • Over 839,000 patients, 12,011 developed depression and 11,828 anxiety.
  • Most psychiatric diagnoses occurred within 90 days, peaking around 3 weeks post-surgery.
  • Opioid use and Medicaid insurance were significant predictors of psychiatric disorders, particularly suicidal ideation.

Conclusions:

  • New-onset psychiatric disorders are frequent early complications following lumbar fusion.
  • Modifiable factors like perioperative opioid use and demographic factors like socioeconomic status predict risk.
  • Structured mental health screening and risk stratification are crucial for early intervention and improved patient outcomes.