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Dual-state emission probes with a decahydroquinoline-naphthalimide skeleton for cells and tissue imaging at low
Qi Lin1, Wen-Pei Ni1, Wen-Juan Gan2
1College of Chemistry, Chemical Engineering and Material Science, Soochow University, No. 199 Ren Ai Road, Suzhou 215123, China. sunru924@hotmail.com.
Abstract:
Polarity-sensitive probes 1a-1c exhibit dual-state emission (DSE) by increasing the twist angle between auxochrome and fluorogen. They can target specific organelles at 200 nM and distinguish cancer cells from normal cells. More importantly, the probes have the ability to differentiate the liver cancer tissue at different stages of differentiation.

