[A Case of Peristomal Abscess after Treatment with Panitumumab]

A 70-year-old woman was diagnosed with rectal cancer Ra, cT3N1bM0, cStage Ⅲa. The patient underwent laparoscopic colostomy. Panitumumab+FOLFOX therapy was initiated as preoperative chemotherapy. Four weeks after the administration of panitumumab, micro-ulcerations developed around the stoma, and panitumumab was withdrawn. Eight weeks after treatment, the patient reported redness, swelling, and pain around the stoma. An abscess was observed draining from the ulceration site, and a CT scan revealed extensive subcutaneous abscess formation around the stoma. Because the tumor had shrunk by 50%, chemotherapy was discontinued, and laparoscopic low anterior resection, colostomy closure, and debridement were performed. Postoperatively, the stoma wound was treated with local negative pressure closure. Regular outpatient visits should be encouraged when chemotherapy is administered to ostomates, particularly when anti-EGFR antibody drugs are administered. Because the area where the faceplate is applied can only be observed in detail during stoma care, it is important to identify skin lesions early. Additionally, it is important to collaborate closely with the WOCN, primary care physicians, and dermatologists.