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Related Concept Videos

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Related Experiment Video

Updated: Jun 22, 2026

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

Reference dosimetry data and machine performance comparison for tomotherapy delivery systems audited by IROC.

Paige A Taylor1,2, Hunter Mehrens1,2, Mallory C Glenn1,2

  • 1Department of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.

Journal of Applied Clinical Medical Physics
|November 18, 2025
PubMed
Summary

This study compiled dosimetry data from nine TomoTherapy units, comparing independent measurements with treatment planning system calculations. The findings offer a valuable reference for verifying TomoTherapy beam commissioning and quality assurance.

Keywords:
TomoTherapyauditquality assurance

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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

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Last Updated: Jun 22, 2026

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07:31

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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Technology

Background:

  • TomoTherapy units are widely used in radiation oncology.
  • Independent dosimetry measurements are crucial for quality assurance.
  • Establishing a dataset of dosimetric properties can aid in performance verification.

Purpose of the Study:

  • To compare Imaging and Radiation Oncology Core (IROC) on-site TomoTherapy dosimetry measurements across institutions.
  • To create a dataset of fundamental dosimetric properties for TomoTherapy machines.
  • To assess agreement between independent measurements and institutional treatment planning system (TPS) calculations.

Main Methods:

  • Collected independent ion chamber measurements for nine TomoTherapy units from 2008 to 2023.
  • Performed measurements including percent depth dose (PDD) in water and off-axis factors (OAF) in a solid phantom.
  • Compared IROC measurements with institutional TPS calculations for each TomoTherapy system.

Main Results:

  • Compiled and tabulated numeric measurement values and comparative ratios for PDD and OAF.
  • Evaluated the distribution of measurements, reporting mean, standard deviation of the mean, and median values.
  • Generated a dataset characterizing the inherent performance of TomoTherapy units.

Conclusions:

  • The compiled data serve as an independent reference for TomoTherapy unit performance.
  • This dataset can assist users in verifying beam model commissioning.
  • The findings support ongoing quality assurance efforts in radiation therapy.