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Sex-Specific Differences and a Predictive Model Based on Clinical and Biochemical Parameters for Minimal Hepatic

Juan José Gallego1,2, Franc Casanova-Ferrer1, Alessandra Fiorillo1

  • 1INCLIVA Biomedical Research Institute, Valencia, Spain.

Liver International : Official Journal of the International Association for the Study of the Liver
|November 19, 2025
PubMed
Summary

Sex influences minimal hepatic encephalopathy (MHE) in cirrhosis patients. Males show higher inflammation and oxidative stress. Sex-specific models improve MHE diagnosis, aiding early intervention for this early stage of hepatic encephalopathy.

Keywords:
early diagnosisinflammationminimal hepatic encephalopathyoxidative stresssex difference

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