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Head and Neck Plasmacytoma With Diffuse Amyloid Deposition: A Case Report
Amirah Alnour1, Mohammad-Aasem Abbas2, Ameen Rahmoun2
1Oral and Maxillofacial Pathology Department, Damascus University, Damascus, Syria.
Case Reports in Dentistry
|November 19, 2025
Summary
This case report details a unique destructive plasmacytoma with amyloid deposition in the mandible, presenting invasive features but a good prognosis. Understanding such rare tumors is key for effective patient management and improved outcomes.
Area of Science:
- Oncology
- Pathology
- Oral and Maxillofacial Surgery
Background:
- Tumor biological profiles evolve due to carcinogens and diagnostic advancements, impacting diagnosis and behavior.
- Plasmacytoma's unpredictable histopathology and clinical behavior necessitate further case documentation for better prognosis prediction.
- Extramedullary plasmacytoma, though rarely progressing to multiple myeloma, poses management challenges due to recurrence potential.
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