Interest in Facial Volume Restorative Procedures With the Rise in "Ozempic Face": A Google Trends Analysis.

Area of Science:

• Medical Aesthetics
• Endocrinology

Background:

• Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely prescribed for type 2 diabetes and obesity.
• GLP-1RA use can lead to facial volume loss and an aged appearance, a phenomenon termed "Ozempic face."

Purpose of the Study:

• To investigate the association between public interest in "Ozempic face" and related aesthetic procedures.
• To determine if increased searches for GLP-1RA side effects correlate with searches for corrective treatments.

Main Methods:

• Analysis of Google Trends data for "Ozempic face" and related terms.
• Statistical correlation between search interest for facial changes and aesthetic procedures (fillers and surgery).

Main Results:

• Significant increase in search trends for "Ozempic face" and related terms from June 2022 to June 2025.
• Positive correlation found between interest in facial weight loss and "filler" procedures.
• No significant correlation observed between interest in facial weight loss and surgical procedures.

Conclusions:

• Clinicians should be aware of the "Ozempic face" phenomenon for patient counseling and management.
• Facial aesthetic procedures, particularly fillers, are increasingly relevant for GLP-1RA users.
• Further research is needed on optimal aesthetic treatments for GLP-1RA-induced facial changes.