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Updated: Jan 11, 2026

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K
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Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K

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Biological J-Coupling Spectroscopy at Low Magnetic Field

Gonzalo G Rodriguez1,2, Charlotte von Petersdorff-Campen1,2, Sergey Korchak1,2

  • 1NMR Signal Enhancement Group Max Planck Institute for Multidisciplinary Sciences Am Fassberg 11 37077 Göttingen Germany.

Small Science
|November 19, 2025
PubMed
Summary

Low-field Nuclear Magnetic Resonance (NMR) spectroscopy now resolves cellular metabolism. This advance uses J-coupling spectroscopy and parahydrogen-induced polarization for benchtop analysis of cancer cell pyruvate metabolism.

Keywords:
J‐couplingcellular metabolismhyperpolarizationlow-field MRImagnetic resonance imagingparahydrogenpyruvate

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