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Updated: Jan 6, 2026

Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
Oscillometry findings in altered spirometry patterns and relationship to respiratory symptoms
Sanna Kjellberg1,2, Ida Åhman3,2, Martin Färdig3
1School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Abnormal impulse oscillometry (IOS) findings are common in individuals with spirometry patterns like preserved ratio impaired spirometry (PRISm) and restrictive spirometry pattern (RSP). These abnormal IOS results help explain respiratory symptoms and increased sick leave in affected patients.
Area of Science:
- Pulmonary medicine
- Respiratory physiology
- Diagnostic imaging
Background:
- Preserved ratio impaired spirometry (PRISm) and restrictive spirometry pattern (RSP) are linked to higher morbidity and mortality.
- The underlying mechanisms for these spirometry patterns remain unclear.
- Impulse oscillometry (IOS) offers sensitive small airway function assessment, surpassing spirometry.
Purpose of the Study:
- To investigate the prevalence of abnormal IOS findings across different spirometry patterns (obstructive, PRISm, RSP).
- To examine the association between abnormal IOS indices and respiratory symptoms.
- To explore the link between abnormal IOS findings, spirometry patterns, and respiratory-related sick leave.
Main Methods:
- Analysis of data from 10,360 participants (aged 50-64) in the Swedish CArdioPulmonary bioImage Study (SCAPIS).
- Simultaneous assessment of IOS and spirometry.
- Questionnaires were used to collect data on respiratory symptoms.
- Reference values were established from healthy, never-smoking participants; abnormality was defined as <5th or >95th percentile.
Main Results:
- Abnormal IOS indices were prevalent across spirometry groups: 31% (obstructive), 38% (PRISm), 28% (RSP), and 40% (PRISm+RSP).
- Abnormal IOS was associated with respiratory symptoms, including wheeze in obstructive and RSP groups, and dyspnoea in the PRISm group.
- Increased respiratory-related sick leave was observed in obstructive and PRISm+RSP groups, with the highest risk in the latter.
Conclusions:
- Abnormal impulse oscillometry (IOS) indices are frequently observed in individuals with abnormal spirometry patterns.
- IOS findings provide a partial explanation for respiratory symptoms experienced by patients with altered spirometry.
- IOS may offer valuable insights into the functional consequences of spirometry abnormalities.
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