Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Should we explore CBD during cholecystectomy in a patient undergone successful ERCP clearance of stones? a new recommendation.

Updates in surgery·2026
Same author

Glycemic trajectory after face-to-face diabetes self-management education: a dose-response meta-analysis.

Diabetes research and clinical practice·2026
Same author

Guillain-Barré Syndrome, Subtype AMAN, Can Only Be Attributed to Lupus Erythematosus if All Infectious Causes Have Been Ruled Out [Response to Letter].

Open access rheumatology : research and reviews·2026
Same author

Infection following foot and ankle surgery : a subanalysis of data captured from the UK Foot and Ankle Thromboembolism (FATE) audit.

The bone & joint journal·2026
Same author

Oral Health Care in the United States.

Dentistry journal·2026
Same author

Biomolecule-Assisted Synthesis of Blue-Emissive Gold Nanoclusters for Sensitive Analysis of Tetracycline Residues in Food and Feed.

ACS omega·2026
Same journal

Performance Management Counters from Live 5G, 4G and 2G Radio Access Network.

Scientific data·2026
Same journal

Establishment of comparative transcriptome dataset related to nitrogen use efficiency in melon.

Scientific data·2026
Same journal

A chromosome-level reference genome assembly of the King Ratsnake (Elaphe carinata).

Scientific data·2026
Same journal

A six-week longitudinal dataset of wearable and self-reported stress measurements in working adults.

Scientific data·2026
Same journal

A Multi-Regional Single-nucleus Atlas of the Huntington's Disease Brain.

Scientific data·2026
Same journal

A multimodal speech-production dataset with time-aligned articulography, EEG, audio, and vocal-tract anatomy.

Scientific data·2026
See all related articles

Related Experiment Video

Updated: Jan 11, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

24.9K

14,441 Genomics-Based Validated Automated Comprehensive Clinicopathologic Correlations for Myeloid Neoplasms.

Ahmed Elsafty1, Yomna Ahmed2, Taher F Halawa3

  • 1PathOlOgics, LLC, Cairo, Egypt. aelnady777@hotmail.com.

Scientific Data
|November 19, 2025
PubMed
Summary
This summary is machine-generated.

This study presents a large dataset of clinicopathologic correlations for myeloid neoplasms, integrating laboratory results for accurate diagnosis and prognosis. The findings enhance the understanding and management of these hematologic malignancies.

More Related Videos

Comparative Lesions Analysis Through a Targeted Sequencing Approach
08:16

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

7.2K
Database-guided Flow-cytometry for Evaluation of Bone Marrow Myeloid Cell Maturation
12:05

Database-guided Flow-cytometry for Evaluation of Bone Marrow Myeloid Cell Maturation

Published on: November 3, 2018

12.2K

Related Experiment Videos

Last Updated: Jan 11, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

24.9K
Comparative Lesions Analysis Through a Targeted Sequencing Approach
08:16

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

7.2K
Database-guided Flow-cytometry for Evaluation of Bone Marrow Myeloid Cell Maturation
12:05

Database-guided Flow-cytometry for Evaluation of Bone Marrow Myeloid Cell Maturation

Published on: November 3, 2018

12.2K

Area of Science:

  • Hematology
  • Oncology
  • Genetics

Background:

  • Myeloid neoplasms (MN) require accurate diagnosis and prognosis.
  • Clinicopathologic correlations (CPCs) integrating laboratory data are crucial for managing MN.
  • Existing datasets may lack comprehensive clinicopathologic and molecular data.

Purpose of the Study:

  • To create and validate a comprehensive dataset of CPCs for myeloid neoplasms.
  • To leverage laboratory results for automated generation of diagnostic and prognostic CPCs.
  • To facilitate research and clinical decision-making in MN.

Main Methods:

  • Compilation of 14,441 CPCs from 10,794 real-world cases.
  • Integration of complete blood counts (CBC), peripheral blood smear (PBS) findings, flow cytometry, and next-generation sequencing (NGS)/polymerase chain reaction (PCR) molecular results.
  • Inclusion of synthetic genomics data for simulating complex cases.
  • Validation by 51 international experts referencing WHO 5th edition guidelines.

Main Results:

  • Dataset includes 243 chronic myeloid leukemia (CML) cases with 257 mutations and 4,567 non-CML MN cases with 7,883 mutations.
  • Analysis of 5,984 benign/inconclusive cases and 3,647 synthetic CPCs.
  • Confirmed 100% medical and clerical accuracy through expert validation.
  • Automated generation of diagnostic and prognostic CPCs using a specialized online platform.

Conclusions:

  • The Elsafty_Reports_of_Myeloid_Neoplasms_2024 dataset provides a robust resource for myeloid neoplasm research.
  • Automated CPC generation from laboratory results improves diagnostic and prognostic accuracy.
  • This validated dataset supports advancements in the understanding and treatment of MN.