Related Experiment Video
Updated: Jan 6, 2026
08:27
A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
3.6K
High-Intensity Interval Training and Moderate-Intensity Continuous Training on Ventricular-Arterial Coupling (VAC) in
Caroline Ferraz Simões1,2, Rogério Toshiro Passos Okawa1,3, João Carlos Locatelli1,4
1Research Group on Systemic Arterial Hypertension, Arterial Stiffness and Vascular Aging, Maringa, Brazil.
Echocardiography (Mount Kisco, N.Y.)
|November 19, 2025
Summary
High-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) both improved ventricular-arterial coupling (VAC) in obese women. However, only HIIT significantly enhanced the elastance-derived VAC measure, suggesting PWV/GLS may be a more sensitive indicator.
Area of Science:
- Cardiovascular Physiology
- Exercise Science
- Obesity Research
Background:
- Obesity is linked to impaired ventricular-arterial coupling (VAC), a crucial determinant of cardiovascular health.
- Understanding the impact of different exercise modalities on VAC is essential for developing effective interventions in obese populations.
Purpose of the Study:
- To compare the effects of 8-week high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) on VAC in young obese women.
- To evaluate two distinct methods for assessing VAC: pulse wave velocity/global longitudinal strain (PWV/GLS) and arterial/ventricular elastance (Ea/Ees).
Main Methods:
- Twenty-four obese women participated in a supervised 8-week aerobic training program, randomly assigned to either HIIT (n=11) or MICT (n=13).
- HIIT involved 4-min intervals at 85%-95% max heart rate (HRmax); MICT involved 41 min continuous exercise at 65%-75% HRmax.
- VAC was measured using PWV/GLS and Ea/Ees ratios.
Main Results:
- Both HIIT and MICT significantly improved the PWV/GLS ratio, indicating enhanced VAC.
- Only HIIT resulted in a significant reduction of the Ea/Ees ratio, suggesting a greater improvement in VAC.
- A strong correlation was found between relative changes in PWV/GLS and Ea/Ees, highlighting their interconnectedness.
Conclusions:
- Both HIIT and MICT effectively improve VAC in young obese women, as measured by the PWV/GLS ratio.
- HIIT demonstrates a superior effect on VAC when assessed by the elastance-derived Ea/Ees ratio.
- The PWV/GLS ratio may be a more sensitive and integrated marker for detecting exercise-induced improvements in VAC compared to Ea/Ees.
Keywords:
aerobic trainingarterial elastanceglobal longitudinal strainoverweightpulse wave velocityventricular elastanceMore Related Videos
07:40Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
Published on: October 10, 2019
7.7K
09:19Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
Published on: February 2, 2019
10.4K
Related Concept Videos
01:20Exercise and Cardiovascular Response
3.8K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.8K
01:17Exercise and Cardiac Output
1.8K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.8K
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
354
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
354
01:26Exercise Stress Test
1.0K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.0K
01:19Cardiac Output I:Effect of Heart Rate on Cardiac Output
2.3K
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
2.3K
01:29Heart Failure II: Pathophysiology
658
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
658