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Updated: Jan 11, 2026
Interfacing Microfluidics with Microelectrode Arrays for Studying Neuronal Communication and Axonal Signal Propagation
Published on: December 8, 2018
Neuroscience research based on microelectrode arrays and microfluidic technology
Wentao Zhang1, Kai Han1, Xiaolu Miao1
1Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, School of Chemistry and Chemical Engineering, Zhengzhou Research Institute, Beijing Institute of Technology, Beijing 100081, PR China.
Abstract:
The combination of microfluidic technology and Microelectrode Arrays (MEAs) provides a powerful tool for neuroscience research. It enables the construction, manipulation, and study of neuronal networks in a controllable in vitro environment, revealing the relationship between their structure and function, and bringing new breakthroughs to fields such as disease modeling, drug screening, and neural interface development. This article will review the relevant research on microfluidic technology and MEA in the field of neuroscience from aspects such as the design principles, preparation, and application research of microfluidic chips and MEA in the neural field.
