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Published on: January 16, 2015
Exploratory Study of Cesarean Scar Healing After Interrupted Versus Continuous Sutures: Prospective Magnetic
Ayako Inatomi1, Shunichiro Tsuji1, Yuri Nobuta1
1Department of Obstetrics and Gynecology Shiga University of Medical Science Otsu Shiga Japan.
Purpose:
This study evaluated the effects of double-layer interrupted sutures (DIS) and double-layer continuous sutures (DCS) on uterine blood flow and residual myometrial thickness (RMT) in cynomolgus monkeys after cesarean section (CS).
Methods:
In DIS (n = 8) and DCS (n = 8) groups, uterine blood flow was assessed at 6 months post-CS using MRI by Ktrans. RMT was measured by T2-weighted magnetic resonance imaging (MRI) at 6 months. Laparoscopic evaluations were performed at 2 and 6 months.
Results:
At 6 months, Ktrans was significantly higher in the DIS group 6. RMT at the suture site did not differ significantly between groups. Adhesions were observed in three DIS and two DCS animals. Nonadhesive DIS animals had significantly higher Ktrans and greater RMT at 6 months compared with adhesive DIS animals. Nonadhesive DIS exhibited significantly higher Ktrans and greater RMT at 6 months than nonadhesive DCS.
Conclusion:
While overall differences were limited, exploratory findings indicate that DIS demonstrated superior uterine blood flow compared with DCS. Nonadhesive DIS animals exhibited greater RMT than adhesive DIS animals, suggesting a potential benefit of adhesion prevention.
