[Unusual bone marrow metastasis revealed by recurrent haematuria]
Hatem Gabsi1, François Audenet2, Virginie Verkarre3
1Laboratoire d'Hématologie Biologique, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.
Abstract:
Bone marrow metastasis of solid tumours is a sign of advanced disease, with their frequency depending on the primary cancer site. Bone marrow metastasis of bladder cancer is an unusual presentation of the disease. We present a case of a patient with non-muscle-invasive bladder cancer, presenting with recurrent macroscopic haematuria after urinary catheterisation leading to discovery of bi-cytopenia on complete blood count. Myelogram realized after sternal bone marrow aspiration showed presence of metastatic cells immunostained for urothelial nature. The clinical course was rapidly unfavorable leading to patient's death shortly after diagnosis. metastasis of bladder cancer to the bone marrow is a highly unusual situation associated with a poor prognosis.
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