Related Experiment Video
Updated: Jan 10, 2026
23:33
The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
84.3K
Thrombus on ASD Closure Device Reveals Underlying Thrombophilia.
Riwad Iftekhar1, Michael McMullan2, William Campbell2
1UMMC School of Medicine, Jackson, Mississippi, USA.
JACC. Case Reports
|November 20, 2025
Summary
Transcatheter closure of atrial septal defects (ASDs) can lead to device-related thrombosis in patients with undiagnosed thrombophilia. Screening for hypercoagulable conditions before ASD closure is crucial to prevent embolic stroke.
Area of Science:
- Cardiology
- Neurology
- Hematology
Background:
- Transcatheter closure of atrial septal defects (ASDs) is a common procedure to prevent paradoxical embolism.
- While major complications are rare, thrombus formation on closure devices can occur, especially in patients with underlying thrombophilia.
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