Related Experiment Video

Updated: Jan 10, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.8K

Birth month as a risk factor of allergic diseases: Analysis of database of about 50 thousand children

Alexander Pampura1,2, Natalia Esakova2, Daria Dolotova2

  • 1Morozov Children's City Hospital, Moscow, Russian Federation.

Plos One
|November 20, 2025
PubMed

Insights

Children born in winter months (December-February) have a higher risk of allergic rhinitis. Those born in October face increased odds of atopic dermatitis, independent of other factors.

Area of Science:

  • Pediatric Allergy and Immunology
  • Environmental Epidemiology
  • Public Health

Background:

  • Season of birth is a known factor influencing neonatal adaptation and allergy risk.
  • Understanding birth month's impact on childhood allergies is crucial for public health initiatives.

Purpose of the Study:

  • To investigate the association between month of birth and the development of allergic diseases in Moscow children.
  • To identify specific birth months linked to increased risk of atopic dermatitis and allergic rhinitis.

Main Methods:

  • Utilized de-identified data from 49,857 children under 18 from Moscow's Unified Medical Information System (2024).
  • Included data on atopic dermatitis, asthma, allergic rhinitis, age, sex, and family history.
  • Employed multivariate logistic regression to calculate adjusted odds ratios (aOR).

Main Results:

  • Children born October-April showed higher odds of allergic rhinitis compared to July, particularly December-February (aOR 1.34-1.39).
  • Births between August-February were linked to increased atopic dermatitis risk versus April, with October showing the highest association (aOR 1.17).
  • Winter births (Dec-Feb) increased allergic rhinitis odds by 34-38%; October births increased atopic dermatitis odds by 16%.

Conclusions:

  • This study is the first in Russia to link specific birth months to elevated allergy risks.
  • Children born in October have higher odds of atopic dermatitis; those born in December, January, or February have higher odds of allergic rhinitis.
  • These associations were independent of sex, age, family history, and co-existing allergic conditions, warranting further research.
Abstract

More Related Videos

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM1010:42

Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10

Published on: November 19, 2016

7.9K
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

16.9K

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.3K
Allergic Reactions02:06

Allergic Reactions

Overview
31.9K
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
774
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.2K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.0K
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
5.0K