Focal Therapies for Localized Prostate Cancer

With the overall technological diagnostic improvement of prostate cancer (PCa), focal therapy has emerged as a promising approach for the treatment of localized PCa, offering in a selected group of patients an intermediate option between active surveillance and radical interventions. The primary goal of focal therapy is to avoid local progression and metastatic disease, and decrease the morbidity associated with whole gland therapy. Selection of energy source and approach depends on the index lesion(s) location, size, prostate anatomy, surrounding structures, overall clinical characteristics, patient expectations, and surgeon experience. Further long-term prospective data assessing the outcomes of focal therapy are still required.