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Clinical Audit Determining Standard of Care for Musculoskeletal Health in Children With Spinal Cord Disorders
Jamie Ellis1,2, Mary P Galea2, Peter Simm1,3
1Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Insights
Pediatric spinal cord disorders (SCD) significantly impact musculoskeletal health, leading to scoliosis, hip dysplasia, and contractures. Nonambulant children face the highest risk of multiple complications.
Area of Science:
- Pediatric Orthopedics
- Neurology
- Rehabilitation Medicine
Background:
- Pediatric spinal cord disorders (SCD) are rare but severe conditions.
- Limited evidence exists on their impact on musculoskeletal health management in children.
- This study addresses this gap by examining SCD characteristics and related complications.
Purpose of the Study:
- To investigate the relationships between spinal cord disorder characteristics and musculoskeletal complications in pediatric patients.
- To identify risk factors associated with specific musculoskeletal issues in children with SCD.
Main Methods:
- Retrospective review of medical records for 100 pediatric patients with SCD (diagnosed 2010-2022).
- Data collected included demographics, SCD etiology (traumatic vs. non-traumatic), and presence of hypercalcemia, fractures, scoliosis, hip dysplasia, spasticity, contractures, and vitamin D status.
- Statistical analysis using odds ratios (OR) and 95% confidence intervals (CI) to assess associations.
Main Results:
- Scoliosis (41%), spasticity (32%), and contractures (27%) were common complications.
- Nonambulant status significantly increased the risk of scoliosis (OR 11.69), hip dysplasia (OR 55.64), contractures (OR 10.72), and spasticity (OR 3.19).
- Hypercalcemia was associated with male patients (OR 4.07) and wheelchair users (OR 6.77).
Conclusions:
- Children with SCD are highly susceptible to diverse musculoskeletal complications.
- Nonambulatory status is a critical risk factor for multiple orthopedic issues.
- Comprehensive data on traumatic and non-traumatic SCD etiologies and their musculoskeletal sequelae are provided.
Background:
Pediatric spinal cord disorders (SCD) are rare and devastating. However, evidence on the effect on musculoskeletal health management is limited.
Objectives:
To investigate the relationships between SCD characteristics and musculoskeletal complications in children with SCD.
Methods:
Medical records of patients admitted between January 2010 and December 2022 with SCD were retrospectively reviewed. Demographic data and the presence of hypercalcemia, fractures, scoliosis, hip dysplasia, spasticity, contractures, calcium, and vitamin D status were obtained (N = 100; male, 61%; median [IQR] age at diagnosis, 9 [9.5] years, range 0-17).
Results:
Traumatic diagnoses represented 36% of patients. Incidence of scoliosis was 41%, hip dysplasia 12%, pathological fractures 9%, spasticity 32%, contractures 27%, hypercalcemia 20%, and vitamin D insufficiency 28% of total. Hypercalcemia was associated with male patients (odds ratio [OR] 4.07, 95% CI 1.03-16.06) and wheelchair users (OR 6.77, 95% CI 1.99-23.84). Nonambulant subjects were at increased risk of having scoliosis (OR 11.69, 95% CI 3.04-44.96), hip dysplasia (OR 55.64, 95% CI 5.59-553.41), contractures (OR 10.72, 95% CI 2.64-43.53), spasticity (OR 3.19, 95% CI 1.14-8.87), and presence of three or more musculoskeletal-related complications (OR 27.03, 95% CI 5.62-130.10).
Conclusion:
Children with SCD are susceptible to many complications related to musculoskeletal health. This research provides comprehensive data on both traumatic and nontraumatic SCD disease etiologies in Victoria, Australia.
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