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Updated: Jan 10, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Copper-catalyzed synthesis of functionalized dithioalkenes from solid calcium carbide
1College of Chemistry and Chemical Engineering/State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, Ningxia University, Yinchuan, 750021, China. yang_jh@nxu.edu.cn.
Abstract:
A complementary strategy employing nucleophilic addition reactions was demonstrated, using calcium carbide as the acetylene source, 2-bromophenylthiophenol as substrate, and copper as catalyst. This approach is distinguished by its reliance on stable, easy-to-handle acetylene surrogates, broad substrate applicability, tolerance to open-air aqueous conditions, and facile scalability to gram-level synthesis.
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