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Reducing Epinephrine Use and Enhancing Documentation for Chemotherapy Hypersensitivity Reactions.
Shavonda Neal1, Jacalyn Buck2, Elizabeth Sharpe3
1Shavonda Neal.
Clinical Journal of Oncology Nursing
|November 21, 2025
Summary
This study assessed how often epinephrine was used for hypersensitivity reactions in thoracic cancer patients. It also evaluated adherence to treatment protocols for these critical events.
Area of Science:
- Oncology
- Clinical Pharmacy
- Quality Improvement
Background:
- Hypersensitivity reactions (HSRs) are a concern in cancer treatment.
- Epinephrine is a critical rescue medication for HSRs.
- Ambulatory care settings require clear protocols for managing HSRs.
Purpose of the Study:
- To determine the frequency of epinephrine use for HSRs in thoracic cancer patients.
- To evaluate adherence to established protocols for HSR management.
- To identify areas for improvement in HSR care within an ambulatory unit.
Main Methods:
- Quality improvement project methodology.
- Retrospective chart review.
- Analysis of medication administration records and clinical notes.
Main Results:
- Data on epinephrine administration frequency was collected.
- Adherence to specific clinical guidelines was assessed.
- The study identified patterns in HSR management.
Conclusions:
- Understanding epinephrine use frequency is key for optimizing HSR management.
- Protocol adherence is crucial for patient safety in ambulatory oncology.
- This project provides insights for enhancing HSR response protocols.
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