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Clinical characteristics and predictor analysis of pediatric Mycoplasma pneumoniae pneumonia with small segment
Baozhou Hong1, Chunfang Li1, Sijun He1
1Department of Pediatrics, Mindong Hospital, Fujian Medical University, Ningde, Fujian, People's Republic of China.
Background:
This study aimed to analyze the clinical characteristics and identify predictive factors associated with small segment molded sputum plugs in pediatric patients with Mycoplasma pneumoniae pneumonia (MPP).
Methods:
A retrospective analysis was performed on the clinical data of pediatric patients diagnosed with MPP who underwent bronchoscopy at our hospital between December 2021 and April 2024. Multivariate logistic regression was employed to determine independent predictors of small segment molded sputum plug formation.
Results:
Among 116 pediatric patients with MPP who met the study criteria, 48 (41.38%) were found to have small segment molded sputum plugs, while 68 (58.62%) did not. Patients with a history of recurrent respiratory infections, diminished breath sounds, and radiological evidence of atelectasis were significantly more likely to develop molded sputum plugs (P < 0.05). Furthermore, the group with small segment molded sputum plugs exhibited a longer duration of fever (P = 0.025) and elevated levels of procalcitonin (PCT; P = 0.024), alanine aminotransferase (ALT; P = 0.048) and prothrombin time (PT; P = 0.021). Multivariate logistic regression analysis identified a history of recurrent respiratory infections and diminished breath sounds as independent predictors for the development of small segment molded sputum plugs.
Conclusions:
A history of recurrent respiratory infections and diminished breath sounds emerged as independent predictors of small segment molded sputum plugs in pediatric MPP. These findings highlight the importance of considering these clinical features during the evaluation of MPP patients to inform diagnostic and therapeutic decision-making. Future studies are warranted to investigate the potential benefits of early detection and intervention on clinical outcomes in pediatric MPP.
Insights
Recurrent respiratory infections and diminished breath sounds predict molded sputum plugs in pediatric Mycoplasma pneumoniae pneumonia (MPP). Early identification of these factors aids in managing MPP cases.
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
- Respiratory Medicine
Background:
- Mycoplasma pneumoniae pneumonia (MPP) is a common pediatric respiratory infection.
- Molded sputum plugs can complicate MPP, impacting clinical course.
- Understanding predictors of these plugs is crucial for effective management.
Purpose of the Study:
- To analyze clinical characteristics of pediatric MPP patients with molded sputum plugs.
- To identify independent predictive factors for small segment molded sputum plug formation in pediatric MPP.
Main Methods:
- Retrospective analysis of clinical data from 116 pediatric MPP patients.
- Bronchoscopy data utilized for diagnosis and plug assessment.
- Multivariate logistic regression applied to identify predictors.
Main Results:
- 41.38% of patients had small segment molded sputum plugs.
- History of recurrent respiratory infections and diminished breath sounds were significant risk factors (P < 0.05).
- Patients with plugs had longer fever duration and elevated PCT, ALT, and PT levels.
Conclusions:
- Recurrent respiratory infections and diminished breath sounds are independent predictors of molded sputum plugs in pediatric MPP.
- These clinical features are vital for guiding diagnosis and treatment decisions.
- Further research on early detection and intervention benefits is recommended.
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