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Three-year Outcomes of Conventional Versus Minimally Invasive Endodontic Treatment Protocols: A Retrospective Study
Kiavash Hossini1, He Liu1, Ya Shen1
1Division of Endodontics, Department of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada.
Journal of Endodontics
|November 23, 2025
Summary
Minimally invasive endodontic protocol (MIEP) with GentleWave (GW) technology showed similar success rates to conventional endodontic treatment (CEP) over 3 years. MIEP/GW also resulted in significantly less postoperative pain.
Area of Science:
- Endodontics
- Dental Technology
- Minimally Invasive Procedures
Background:
- Comparison of conventional endodontic treatment (CEP) and minimally invasive endodontic protocol (MIEP) using GentleWave (GW) technology.
- Evaluation of 3-year clinical and radiographic outcomes.
Purpose of the Study:
- To compare the 3-year outcomes of MIEP/GW versus CEP.
- To assess success rates and postoperative pain incidence.
Main Methods:
- Retrospective study of 114 patients in 2 endodontic clinics.
- MIEP/GW and CEP groups received different obturation techniques and bioceramic sealers.
- Clinical and radiographic evaluations at 36 months; data analyzed using Chi-square or Fisher's exact test.
Main Results:
- 96.5% recall rate (110/114 patients) at 36 months.
- MIEP/GW group had significantly lower moderate/severe postoperative pain (P < .05).
- Comparable success rates: MIEP/GW (88.7% loose, 69.4% strict) vs. CEP (81.3% loose, 54.2% strict) (P > .05).
Conclusions:
- MIEP/GW protocol demonstrated comparable success rates to CEP.
- MIEP/GW showed a reduced incidence of moderate or severe postoperative pain.
- MIEP with GW technology is a viable alternative to conventional endodontic treatment.

