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Updated: May 3, 2026

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
Rhabdomyomatous Mesenchymal Hamartoma: An Acquired Plaque-Type Variant Case Report
Robyn Okereke1, Anthony Linfante2
1Oregon Health & Sciences University, Department of Dermatology, Portland, Oregon, United States.
Abstract:
Rhabdomyomatous Mesenchymal Hamartoma (RMH) is a rare, typically congenital, benign hamartomatous tumor of the dermis and subcutaneous tissue. The lesions consist of disordered collections of mature skeletal muscle and varying amounts of additional mesenchymal-derived tissue. RMH is usually a solitary, polypoid, midline lesion of the head or neck in an infant or child, which may occur in conjunction with multiple ectodermal/mesodermal abnormalities. More recently, patterns of RMH occurring in adults have been described. Herein, we present an adult patient who presented with an RMH on the chin, followed by a clinical course and histologic evaluation. This case demonstrates an uncommon variant of an acquired, plaque-type RMH with unique histologic properties.
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