When Pneumonia Isn't the Whole Story: A Diagnostic Challenge in Septic Shock

Pedro Pires Mesquita1, Gonçalo Torrinha2, Vânia Gomes1

  • 1Internal Medicine, Unidade Local de Saúde de Braga, Braga, PRT.

Cureus
|November 24, 2025
PubMed

Insights

Immunocompromised patients with septic shock may have unusual causes. A case highlights how a foreign body in the colon, alongside pneumonia, complicated diagnosis and management in a rheumatoid arthritis patient.

Area of Science:

  • Critical Care Medicine
  • Gastroenterology
  • Rheumatology

Background:

  • Septic shock in immunocompromised patients often stems from common infections.
  • Patients on immunosuppressive therapy (e.g., corticosteroids, methotrexate) for conditions like rheumatoid arthritis are at higher risk.
  • Overlapping symptoms can complicate clinical reasoning and management.

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