Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

7.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
7.1K
The Thyroid Gland01:23

The Thyroid Gland

6.6K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.6K
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

374
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
374
The Parathyroid Glands00:59

The Parathyroid Glands

4.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
4.2K
Relative Risk01:12

Relative Risk

1.8K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
1.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

4.9K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lifestyle-Induced Visceral Fat Loss as a Key Target for Durable Cardiometabolic Health: MRI-Assessed 5- and 10-Year Follow-Up After 2 Clinical Trials.

Circulation·2026
Same author

Sustained visceral fat loss is associated with attenuated brain atrophy and improved cognitive function in late midlife.

Nature communications·2026
Same author

Predicting chronic subdural hematoma risk in elderly patients with mild traumatic brain injury.

Acta neurochirurgica·2026
Same author

Predicting Repetitive Negative Thinking in Daily Life: Insights From Brain-Based Graph-Theoretical Predictive Modeling.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2025
Same author

Comparative analysis of osteoclast function in symptomatic and asymptomatic individuals with cherubism-causing SH3BP2 mutation.

JBMR plus·2025
Same author

Dopaminergic frontostriatal pathways in major depressive disorder and childhood sexual abuse: a multimodal neuroimaging investigation.

Molecular psychiatry·2025

Related Experiment Video

Updated: Jan 10, 2026

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
06:08

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Published on: June 2, 2023

2.2K

Parity as a Risk Factor for Differentiated Thyroid Carcinoma: A Population-based Study.

Rotem Dan1, Nave Paran2, Nuphar Vinegrad3,4

  • 1The Goldman Medical School at the Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105 Beer Sheva, Israel.

The Journal of Clinical Endocrinology and Metabolism
|November 24, 2025
PubMed
Summary

High parity, defined as four or more deliveries, is linked to an increased risk of differentiated thyroid carcinoma (DTC) in women. This association was particularly evident in Arab women within a high-multiparity population.

Keywords:
differentiated thyroid cancermultiparitypapillary thyroid carcinomaparity

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

922
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

4.7K

Related Experiment Videos

Last Updated: Jan 10, 2026

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
06:08

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

Published on: June 2, 2023

2.2K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

922
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

4.7K

Area of Science:

  • Endocrinology
  • Reproductive Health
  • Oncology

Background:

  • Female sex is a known risk factor for differentiated thyroid carcinoma (DTC).
  • Reproductive influences are suspected contributors, but data on parity and DTC risk are inconsistent.

Purpose of the Study:

  • To investigate the association between parity and DTC risk.
  • Focus on a population characterized by high multiparity.

Main Methods:

  • Population-based case-control study (1982-2022) at a single tertiary medical center.
  • Included 300 female DTC cases and 900 controls, matched by birth year and ethnicity.
  • Logistic regression analysis adjusted for socioeconomic status, TSH levels, oral contraceptive use, and autoimmune thyroid diseases.

Main Results:

  • DTC diagnosis median age was 39 years; 60% Jewish, 40% Arab.
  • Increased DTC risk observed with four or more deliveries (OR=1.70) and six or more (OR=1.89).
  • Association primarily driven by Arab women with higher grand multiparity rates.

Conclusions:

  • High parity, specifically four or more deliveries, is associated with elevated DTC risk.
  • The association is more pronounced in Arab women.
  • Findings highlight the role of reproductive history in DTC risk stratification.