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Effects of LP.8.1-adapted mRNA vaccination on SARS-CoV-2 variant neutralisation

Christine Happle1, Markus Hoffmann2, Metodi V Stankov3

  • 1Department of Rheumatology and Immunology, Hannover Medical School, Hannover 30625, Germany; Department of Pediatric Pulmonology, Allergology, and Neonatology, Hannover Medical School, Hannover 30625, Germany; German Center for Lung Research, Biomedical Research in End-stage and Obstructive Lung Disease Hannover (BREATH), Hannover, Germany.

The Lancet. Infectious Diseases
|November 24, 2025
PubMed
Summary

No abstract available in PubMed .

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Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...