Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Translocation of Proteins into the Mitochondria

Translocation of Proteins into the Mitochondria

Mitochondrial precursors are translocated to the internal subcompartments via independent mechanisms involving distinct protein machineries called translocases.
Sorting of outer membrane proteins:
Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Thrombospondin-2 deficiency primes the synovial joint for aberrant tissue remodeling and injury response.

bioRxiv : the preprint server for biology·2026

Same author

Patterns of Muscle Health in Single- and Multi-Site Chronic Pain: A UK Biobank Normative Modeling Study.

medRxiv : the preprint server for health sciences·2026

Same author

Shared neural geometries for bilingual semantic representations in human hippocampal neurons.

Cell·2026

Same author

Wnt/β-catenin signaling regulates fibrotic atrophy of intra-articular adipose tissue in post-traumatic osteoarthritis.

bioRxiv : the preprint server for biology·2026

Same author

Immune Aging is an Independent Risk Factor for Cardiovascular Disease.

bioRxiv : the preprint server for biology·2026

Same author

Detecting Features of Interpersonal Difficulties in First-Person Accounts of Schizophrenia; Automated Linguistic and Network Analyses.

Schizophrenia bulletin open·2026

Same journal

Retsat promotes synovial mesenchymal stem cell senescence and aggravates osteoarthritis by inhibiting the PPARγ/RXR heterodimerization pathway.

Osteoarthritis and cartilage·2026

Same journal

Effectiveness of a blended care intervention in physiotherapy with exercise and education for patients with hip or knee osteoarthritis (SmArt-E): A multicentre pragmatic randomized controlled trial.

Osteoarthritis and cartilage·2026

Same journal

Through the lens of light sheet, knee innervation shines.

Osteoarthritis and cartilage·2026

Same journal

Deep learning-based quantification of knee effusion-synovitis volume on MRI - Technique development and validation.

Osteoarthritis and cartilage·2026

Same journal

Mapping articular cartilage maturation across postnatal development by proteomics.

Osteoarthritis and cartilage·2026

Same journal

Effect of an oral complementary medicine combination for symptomatic knee osteoarthritis: A double-blind, randomized, placebo-controlled trial.

Osteoarthritis and cartilage·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 10, 2026

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution

Published on: May 5, 2023

Rethinking mitochondria in scRNAseq analysis

Brian Kim¹, Alexander J Knights²

¹The Kolling Institute, The University of Sydney, Faculty of Medicine and Health & The Northern Sydney Local Health District, St Leonards, NSW, Australia; School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.

Osteoarthritis and Cartilage

|November 24, 2025

Summary

No abstract available in PubMed .

More Related Videos

Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation

Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation

Published on: March 14, 2014

Author Spotlight: Two-Step Tag-Free Isolation of Mitochondria for Improved Protein Discovery and Quantification

Author Spotlight: Two-Step Tag-Free Isolation of Mitochondria for Improved Protein Discovery and Quantification

Published on: June 2, 2023

Related Experiment Videos

Last Updated: Jan 10, 2026

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution

Published on: May 5, 2023

Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation

Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation

Published on: March 14, 2014

Author Spotlight: Two-Step Tag-Free Isolation of Mitochondria for Improved Protein Discovery and Quantification

Author Spotlight: Two-Step Tag-Free Isolation of Mitochondria for Improved Protein Discovery and Quantification

Published on: June 2, 2023