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Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Concise Synthesis of Allylic Sulfones via a Metal-Free Multicomponent Strategy
Zhenlei Zhang1, Yiyuan Sheng1, Yixuan Cui1
1School of Chemistry and Material Engineering, Anhui Provincial Key Laboratory of Green Carbon Chemistry, Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions, Biomass-Derived Functional Oligosaccharides Engineering Technology Research Center of Anhui Province, Fuyang Normal University, Fuyang, Anhui 236037, P. R. China.
Abstract:
A practical one-pot, tetramolecular, three-component reaction has been developed for the synthesis of allylic sulfone derivatives. This efficient protocol employs readily available quinoline (ketone) derivatives, sodium sulfinates, and paraformaldehyde, furnishing allylic sulfones in high yields. The reaction features a broad substrate scope, excellent tolerance for diverse functional groups, and scalability, offering a versatile and sustainable approach for the construction of structurally diverse allylic sulfones.
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