Related Experiment Video
Updated: Jan 10, 2026

HKUST-1 as a Heterogeneous Catalyst for the Synthesis of Vanillin
Published on: July 23, 2016
Keplerate-Type Polyoxometalate Anchored on HKUST-1 Derivatives as a Robust Heterogeneous Catalyst for Synthesis of
Mingliang Li1, Yongbin Song1, Lu Bai1
1School of Materials Science and Chemical Engineering, Harbin University of Science and Technology, Harbin 150040, P. R. China.
Abstract:
Functionalized benzoquinones (p-BQs) are essential intermediates in biomedicine and fine chemical synthesis due to their structural diversity and broad chemical reactivity. The development of highly efficient heterogeneous catalysts for their selective production is therefore of considerable importance. In this work, we report a new heterogeneous catalyst, Mo72V30/CuOx/C, prepared by immobilizing a V-substituted Keplerate-type polyoxometalate (POM), Na8K16(VO)(H2O)5[K10⊂{(Mo)Mo5O21(H2O)3(SO4)}12(VO)30(H2O)20]·150H2O (Mo72V30), onto a HKUST-1-derived CuOx/C support. The Mo72V30/CuOx/C catalyst exhibited exceptional activity in the oxidation of 2,3,6-trimethylphenol (TMP), achieving a conversion of over 99% and a yield of 95.3% within only 2 min, while maintaining high performance over five consecutive cycles. Until now, this represents the highest catalytic efficiency reported to date for this transformation. The exceptional catalytic performance stems from the catalyst's high surface area with porous structure, which is beneficial for TMP adsorption and activation, and the strong synergy among its multiple active centers that boosts reaction activity. DFT calculations further elucidated a cooperative dual-active-center mechanism at the atomic level.
Related Concept Videos
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
Radical Chain-Growth Polymerization: Overview
Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
Reactions at the Benzylic Position: Oxidation and Reduction
Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)