Homeopathic Treatment Outcomes in Tinea Corporis and Tinea Cruris-A Multicentric, Open-Label, Prospective,...

Dermatophytosis, particularly tinea corporis and tinea cruris, is a frequent superficial fungal infection, especially in tropical and humid regions. Conventional antifungal treatments, including topical or oral antifungals, may cause side effects, especially with long-term use. Increasing cases of recurrent dermatophytosis and antifungal resistance have prompted the exploration of alternative, safer treatment options.

The study aims to evaluate the effectiveness of individualized homeopathic medicines (IHMs) for the treatment of tinea corporis and cruris.

The study was conducted at four Homeopathy Outpatient Departments from August 2021 to March 2024. Patients with clinically diagnosed tinea corporis or cruris, confirmed by positive potassium hydroxide (KOH) mount test, were included. IHMs were prescribed based on symptom totality and repertorization. The primary outcome was assessed using a Clinical Cure Scale, which evaluates lesion's resolution, itching, and infection clearance. Mycological assessment was conducted to detect the presence or absence of fungus. The Skindex-16 questionnaire measured the impact of skin disease on quality of life (QoL). Assessments were performed at baseline and monthly, until resolution or for up to six months.

A total of 147 patients (mean age of 38.92±12.09 years) were analyzed. Tinea corporis was most prevalent (47%), followed by mixed tinea corporis and cruris (30%) and tinea cruris (23%). After six months, statistically significant improvements were observed in Clinical Cure Scale scores (7.01±1.73 to 2.90±2.66, P < .001) and Skindex-16 scores (from 56.04±25.34 to 27.03±28.99, P < .001). 93 patients (63.3%) tested KOH-negative at the end of treatment. Commonly prescribed medicines included Sulphur (35%), Natrum muriaticum (24%), Sepia (13%), Arsenicum album (11%), Lycopodium clavatum (4%), and Graphites (3%).

The findings support the effectiveness of IHMs in managing dermatophytosis. Rigorous clinical and QoL assessments confirm therapeutic benefits. Future randomized controlled trials and long-term follow-up are recommended to validate these results and assess recurrence.

tinea corporis, tinea cruris, KOH mount, Skindex-16, homeopathy.