Related Experiment Video
Updated: Jan 10, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
Published on: November 24, 2020
Triglyceride to High-Density Lipoprotein Ratio and the Risk of Major Adverse Cardiovascular Events in a Non-Diabetic
Jianmei Wu1, Qi Qi2, Xinyu Wu2
1Department of Cardiovascular Surgery, Tangshan Gongren Hospital.
Abstract:
Objective This study aimed to investigate the role of the triglyceride to high-density lipoprotein cholesterol (TG / HDL-C) ratio for the prediction of major adverse cardiovascular events (MACEs) in non-diabetic individuals.Material and methods In total 88946 non-diabetic individuals were enrolled in the study. These individuals were divided into four groups according to the TG / HDL-C ratios. The clinical endpoints were composite MACEs and their subtypes, myocardial infarction and stroke. Cox proportional hazards regression models and restricted cubic spline (RCS) analysis were conducted to explore the relationship between the TG / HDL-C ratio and MACEs.Results Multivariable Cox proportional hazards analyses showed that a higher TG / HDL-C ratio was associated with an elevated risk of MACEs. Kaplan-Meier survival curve showed that participants in higher quartiles of TG / HDL-C ratio had a higher cumulative incidence of composite MACEs (p<0.0001). In addition, RCS analysis indicated that the TG / HDL-C ratio and composite MACEs followed a non-linear relationship (p<0.0001).Conclusions The TG / HDL-C ratio can serve as a prognostic marker of MACEs in non-diabetic individuals.
More Related Videos
07:29Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
11:13Enrichment of Native Lipoprotein Particles with microRNA and Subsequent Determination of Their Absolute/Relative microRNA Content and Their Cellular Transfer Rate
Published on: May 9, 2019
Related Concept Videos
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Coronary Artery Disease IV: Preventive Measures
Atherosclerosis III: Management
Cholesterol: Significance and Regulation
Considering cholesterol and...
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipids: Dietary Sources and Requirements