LatAtk: A Medical Image Attack Method Focused on Lesion Areas with High Transferability
Long Li1,2, Yibo Huang1,3, Chong Li3
1Joint International Research Laboratory of Spatio-Temporal Information and Intelligent Location Services, Guilin University of Electronic Technology, Guilin 541004, China.
Journal of Imaging
|November 26, 2025
Summary
Researchers developed LatAtk, a novel adversarial attack method for medical images. This method targets lesion areas to improve deep neural network (DNN) security and reliability in healthcare applications.
Area of Science:
- Medical Imaging
- Deep Learning Security
- Adversarial Attacks
Background:
- Concerns regarding the security and reliability of deep learning models in sensitive healthcare applications are rising.
- Adversarial attacks pose a significant threat to the integrity of deep neural networks (DNNs), particularly in medical imaging.
- Existing attack methods lack sufficient transferability and concealment, necessitating advanced security solutions.
Purpose of the Study:
- To propose a novel adversarial attack method, LatAtk, specifically designed for medical images.
- To enhance the security and controllability of DNNs used in life and health safety applications.
- To improve the transferability and concealment of adversarial attacks against medical image analysis.
Main Methods:
- LatAtk utilizes image segmentation to differentiate between attackable (lesion) and non-attackable areas within medical images.
- Perturbations are strategically injected into lesion areas to disrupt DNN attention mechanisms.
- A class activation loss function (Gradient-Weighted Class Activation Mapping) and a texture feature loss function (Local Binary Patterns) are employed to enhance transferability and preserve image integrity.
Main Results:
- LatAtk demonstrated superior aggressiveness in disrupting DNNs compared to existing methods.
- The proposed method exhibited high transferability, effectively attacking different DNN models.
- LatAtk achieved improved concealment, preserving essential texture features and reducing detectability of adversarial samples.
Conclusions:
- LatAtk presents a significant advancement in adversarial attack methodologies for medical imaging.
- The technique offers enhanced security and reliability for DNNs in critical healthcare scenarios.
- Further research into LatAtk can drive innovation in robust defense mechanisms for medical AI.
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