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The Impact of Digital Intervention Messages Targeting Users With High Blood Pressure Events: Retrospective Real-World
Yifat Fundoiano-Hershcovitz1, Inbar Breuer Asher1, Marilyn D Ritholz2
1DarioHealth, Hatarshish 5, North Industrial Park, Caesarea, Israel, 972-47704044.
JMIR Cardio
|November 26, 2025
Summary
Digital health interventions effectively manage hypertension. Data-driven nudges improved blood pressure (BP) in high BP users and maintained stability in normal BP users, showing promise for scalable self-care.
Area of Science:
- Digital Health
- Cardiovascular Health
- Public Health
Background:
- Hypertension management is a public health challenge, with low blood pressure (BP) control rates.
- Scalable digital health interventions are needed to improve BP awareness, behavior change, and clinical outcomes.
- Limited real-world evidence exists on the impact of digital interventions on BP and its mechanisms.
Purpose of the Study:
- To evaluate the effectiveness of a digital intervention using data-driven nudges on monthly average BP levels.
- To assess BP changes before and after the intervention in high and normal BP cohorts.
- To compare intervention effects against a control group.
Main Methods:
- Retrospective real-world cohort study of 408 users from a digital health platform.
- Propensity score matching compared intervention users to non-users across high and normal BP cohorts.
- Piecewise mixed-effects models analyzed monthly average BP trajectories, with simple slope analysis for lifestyle activity moderation.
Main Results:
- In the high BP cohort, the intervention group showed a significant SBP decrease (B=-2.09; P<.001) compared to controls (B=-1.06; P=.007).
- Higher lifestyle activity levels correlated with greater SBP reduction in the intervention group (B=-5.27; P<.001).
- In the normal BP cohort, the intervention group maintained stable BP (B=-0.39; P=.27), while controls saw an increase (B=0.69; P=.03).
Conclusions:
- Data-driven nudges via digital platforms improve BP outcomes in high BP individuals and maintain stability in normal BP individuals.
- These findings support integrating personalized digital interventions into hypertension management.
- Positive messaging, behavioral engagement, and user empowerment are key for long-term hypertension outcomes.
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