Gastric secretion with feeding and restraint in conscious rhesus monkeys

Four chair-housed rhesus monkeys (Macaca mulatta) were surgically prepared with vagally-innervated fundic gastric pouches. As in man, basal acid secretion was evident in all subjects. In response to a test meal, acid output rose twofold over basal values and remained elevated up to 6 h. Compared to control values, food-stimulated acid output was reduced significantly during periods of restraint.