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Improved Postexercise Rehydration With a Milk Permeate-Based Sports Drink.

Tanner L Boro1, Sajjad Rezaei1, Isabela E Kavoura1

  • 1Hydration Science Lab, College of Health Solutions, Arizona State University, Phoenix, AZ, USA.

International Journal of Sport Nutrition and Exercise Metabolism
|November 26, 2025
PubMed
Summary
This summary is machine-generated.

A novel milk permeate-based sports drink (MPSD) significantly improved post-exercise rehydration compared to traditional sports drinks (TSD), high-potassium sports drinks (HKSD), and water (W). MPSD demonstrated superior net fluid balance and reduced urine output, aiding recovery.

Keywords:
electrolytefluid retentionhydration

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Area of Science:

  • Exercise Physiology
  • Sports Nutrition
  • Hydration Science

Background:

  • Effective rehydration is crucial for athletes to restore fluid balance post-exercise.
  • Traditional sports drinks and water have varying rehydration efficacies.
  • Novel ingredients like milk permeate may offer enhanced hydration benefits.

Purpose of the Study:

  • To compare the rehydration efficacy of a milk permeate-containing sports drink (MPSD) against traditional sports drink (TSD), high-potassium sports drink (HKSD), and water (W).
  • To assess fluid balance, urine output, and plasma volume restoration following exercise-induced dehydration.

Main Methods:

  • Twelve healthy adults underwent a 2-hour exercise dehydration protocol in heat, losing ~2% body weight.
  • Participants rehydrated over 4 hours, consuming 150% of lost body weight via TSD, HKSD, MPSD, or water.
  • Measurements included net fluid balance, cumulative urine volume, osmotic excretion, and plasma volume.

Main Results:

  • MPSD resulted in significantly higher net fluid balance at 180 and 240 minutes compared to TSD, HKSD, and W.
  • MPSD led to lower cumulative urine volume than HKSD, TSD, and W.
  • While TSD showed better plasma volume restoration at 60 minutes, MPSD exhibited superior overall rehydration metrics.

Conclusions:

  • A milk permeate-based sports drink is more effective for post-exercise rehydration than TSD, HKSD, and water.
  • MPSD's high osmolality may contribute to its enhanced fluid retention.
  • Further research into MPSD formulations for optimal athletic recovery is warranted.