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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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An innovative AI-based dual segmentation application for head surgery.

M Beyer1, A Brasse1, S Abazi1

  • 1Department of Oral and Craniomaxillofacial Surgery and 3D Print Lab, University Hospital Basel, Basel, Switzerland; Medical Additive Manufacturing Research Group (Swiss MAM), Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland.

International Journal of Oral and Maxillofacial Surgery
|November 26, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a dual-model artificial intelligence (AI) system for automated craniofacial segmentation in CT scans. The AI system significantly reduces manual segmentation time while maintaining clinical accuracy for surgical planning.

Keywords:
Artificial intelligenceTomography

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Area of Science:

  • Medical imaging analysis
  • Artificial intelligence in healthcare
  • Computational anatomy

Background:

  • Accurate anatomical segmentation in CT imaging is crucial for head and neck surgery diagnostics and surgical planning.
  • Manual segmentation is labor-intensive, time-consuming, and prone to inconsistencies.

Purpose of the Study:

  • To develop and validate a dual-model AI system for automated segmentation of craniofacial structures in CT scans.
  • To assess the accuracy and robustness of the AI system compared to manual segmentation.

Main Methods:

  • A two-stage nnU-Net-based AI approach was employed, utilizing a coarse global model and a fine local model.
  • 388 clinical CT scans were processed, with segmentations evaluated using Dice Similarity Coefficient (DSC), Mean Surface Distance (MSD), and Hausdorff Distance (HD).

Main Results:

  • The AI system achieved high accuracy, with mean DSC scores of 0.963 for mandible/skull and 0.986 for soft tissue.
  • Low Mean Surface Distance values were observed for maxillary sinus (0.134 mm) and mandible (0.150 mm).
  • The system demonstrated robustness across diverse imaging protocols, including low-resolution scans.

Conclusions:

  • The dual-model AI system automates craniofacial segmentation efficiently and accurately, reducing manual effort.
  • This open-access framework provides a scalable solution for diagnostic, surgical, and educational applications in craniofacial care.
  • The AI system ensures clinical precision, supporting improved patient outcomes in head and neck surgery.