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A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
Published on: January 6, 2023
Quantifying and modeling respirable dust and crystalline silica exposure in rice mills using the CART algorithm
Muskan Saini1, Immad A Shah2, Srushti Thasale1
1Chemical Sciences Division, ICMR-National Institute of Occupational Health, Ahmedabad, Gujarat, India.
Respirable dust (RD) and respirable crystalline silica (RCS) levels in Indian rice mills were quantified. Operational activities, especially dehusking, significantly impacted exposures, necessitating improved dust control measures.
Area of Science:
- Occupational Health
- Environmental Science
- Industrial Hygiene
Background:
- Rice milling generates significant airborne dust, posing potential respiratory health risks to workers.
- Quantifying exposure to respirable dust (RD) and respirable crystalline silica (RCS) is crucial for assessing occupational hazards in this sector.
Purpose of the Study:
- To quantify RD and RCS exposure levels in Western Indian rice mills.
- To evaluate the association between these exposures and different rice varieties and operational activities.
- To utilize the Classification and Regression Trees (CART) algorithm for handling missing data.
Main Methods:
- Collection of 50 RD samples from workers' breathing zones across mills processing various rice types.
- Quantification of corresponding RCS levels.
- Statistical analysis using Minitab and R, including CART imputation for missing data.
Main Results:
- Operational activities significantly influenced RD (22.55%) and RCS (10.59%) variability (p < 0.05).
- Dehusking operations showed the highest RD and RCS concentrations, while sieving had the lowest.
- Rice varieties had a minimal impact, though Kolam and Parimal showed higher RCS than IR-8, remaining within occupational limits.
Conclusions:
- Operational activities are key drivers of RD and RCS exposure in rice mills, with dehusking being a high-risk task.
- RD and RCS levels in this study were lower than reported in existing literature, potentially due to advanced technology and regional factors.
- Enhanced dust control measures are essential, particularly during high-exposure tasks, and further research with additional environmental data could refine predictive models.
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