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Deep Learning for Sex Estimation from Whole-Foot X-Rays: Benchmarking CNNs for Rapid Forensic Identification
Rukiye Çiftçi1, İpek Atik2, Özgür Eken3
1Department of Anatomy, Medical Faculty, Gaziantep Islam Science and Technology University, Gaziantep 28010, Turkey.
Diagnostics (Basel, Switzerland)
|November 27, 2025
Summary
Deep learning on foot radiographs accurately estimates sex, outperforming traditional methods. This offers a rapid, cost-effective forensic identification tool when DNA analysis is not feasible.
Area of Science:
- Forensic Anthropology
- Medical Imaging
- Artificial Intelligence
Background:
- Accurate sex estimation is vital in forensic identification, especially with fragmented remains or when DNA analysis is impractical.
- Traditional methods using single bone measurements have limitations in accuracy.
- Automated sex estimation using advanced imaging techniques remains an underexplored area.
Purpose of the Study:
- To evaluate the efficacy of deep convolutional neural networks (CNNs) for automated sex estimation.
- To utilize entire foot radiographs as the primary data source for sex estimation.
- To compare the performance of various CNN architectures for this task.
Main Methods:
- Retrospective collection of 471 adult foot radiographs (238 male, 233 female).
- Training six CNN architectures (AlexNet, ResNet-18/50, ShuffleNet, GoogleNet, InceptionV3) via transfer learning with data augmentation.
- Performance evaluation using accuracy, sensitivity, specificity, precision, and F1-score.
Main Results:
- The InceptionV3 CNN model achieved the highest accuracy at 97.1%, with high sensitivity (97.5%) and specificity (96.8%).
- ResNet-50 also demonstrated strong performance with 95.7% accuracy.
- These deep learning models significantly surpassed the accuracy of traditional anthropometric methods (typically 72-89%).
Conclusions:
- Deep learning models applied to whole-foot radiographs provide state-of-the-art accuracy for sex estimation.
- This automated approach offers a rapid, reproducible, and cost-effective solution for forensic identification.
- It is particularly valuable in mass disaster scenarios or clinical emergencies where DNA analysis may be delayed or unavailable.
