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Lacrimal Sac Tumors: A Histotype-Driven Literature Review
Luca Giovanni Locatello1, Enrico Redolfi De Zan2, Riccardo Marzolino1
1Department of Otorhinolaryngology, Academic Hospital "Santa Maria della Misericordia", Azienda Sanitaria Universitaria Friuli Centrale, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.
Objectives:
Because of their rarity, lacrimal sac tumors (LSTs) are challenging to diagnose and treat. We herein provide an overview of the recent literature.
Methods:
A scoping search of the Cochrane library, PubMed and Google Scholar database in the last 5 years was conducted. Three independent reviewers extracted data, and the findings were summarized due to study heterogeneity.
Results:
A total of 55 articles were included. LST histology is diverse and there is no commonly accepted staging system. Recent discoveries in their biology are offering new treatment strategies but exclusive endoscopic resections remain feasible in only very limited cases of non-aggressive LSTs.
Conclusion:
LSTs require a high index of suspicion because of their rarity. A histotype-driven treatment plan must be carefully prepared, but complete excision remains the cornerstone of treatment in all cases.
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