Botulinum Toxin in the Therapy of Chronic or Relapsing Plantar Fasciitis-A Descriptive Review

Background. Plantar fasciitis is a degenerative condition that may follow a chronic or recurrent course. Injectable agents are frequently employed to alleviate pain and restore function. Recently, botulinum toxin (BoNT) has gained particular attention for its analgesic properties, positioning it as a promising therapeutic option for the management of plantar fasciitis. Method. We conducted a literature review to evaluate studies on BoNT administration in plantar fasciitis, aiming to define the target tissues, optimal doses, methods of administration, and associated adverse effects. Results. The evidence suggests that BoNT provides significant short- and long-term analgesic benefits when administered either intrafascially or intramuscularly, with outcomes comparable to or exceeding those of corticosteroids. Conclusion. Further high-quality studies are warranted to compare BoNT with other therapeutic modalities, such as PRP and extracorporeal shockwave therapy (ESWT).