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Fixation Stability as a Surrogate for Reading Abilities in Age-Related Macular Degeneration: A Perspective
Carolina Molin1, Edoardo Midena1,2, Enrica Convento1
1Department of Neuroscience-Ophthalmology, University of Padova, 35128 Padova, Italy.
None:
Age-related macular degeneration (AMD) significantly impacts central vision, fixation site and stability and reading abilities. This work aims to analyze the relationship between retinal fixation parameters measured using microperimetry and reading performance in patients with AMD. We identified the role of fixation stability measurement in the evaluation of reading abilities and discussed its implications both in clinical practice and in clinical trials. Our analysis highlights the importance of retinal fixation assessment as a precise surrogate for evaluating reading ability outcomes in AMD patients and as new clinical endpoint to demonstrate the functional effects of present and emerging target therapies.
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