Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.9K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

969
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
969
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

504
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
504
Other Nuclides: 31P, 19F, 15N NMR01:16

Other Nuclides: 31P, 19F, 15N NMR

705
Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
705
Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule01:10

Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule

2.4K
In the AX proton spin system, proton A can sense the two spin states of a coupled proton X, resulting in a doublet NMR signal with two peaks of equal (1:1) intensity. When proton A is coupled to two equivalent protons (AX2 spin system), the spin states of each X can be aligned with or against the external field, creating three possible scenarios. This results in a 1:2:1  triplet signal, where the central peak corresponds to the chemical shift of A and is twice as large or intense as the...
2.4K
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

215
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
215

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-time AI integration for MR to detect artifacts and guide pulse sequence adaptations.

bioRxiv : the preprint server for biology·2026
Same author

Correction: Detection of regional metabolic alteration using 7T deuterium metabolic imaging in MRI-negative, <sup>18</sup>FDG-PET-positive epilepsy patients.

Magma (New York, N.Y.)·2026
Same author

Structural Fiber Tract Alterations in Relation to Surgery in Children With a Posterior Fossa Tumor.

NMR in biomedicine·2026
Same author

Detection of regional metabolic alteration using 7T deuterium metabolic imaging in MRI-negative, <sup>18</sup>FDG-PET-positive epilepsy patients.

Magma (New York, N.Y.)·2026
Same author

Longitudinal cohort study of muscle function and metabolic biomarkers in disease-modifying treatment of spinal muscular atrophy.

Journal of neuromuscular diseases·2026
Same author

Distribution of Somatostatin and Its Receptors in the Intestinal Tract in Healthy Patients and Patients with Type 2 Diabetes.

The Journal of clinical endocrinology and metabolism·2025
Same journal

Multi-Contrast Human Brain CEST MRI at 11.7 T: First In Vivo Demonstration.

Magnetic resonance in medicine·2026
Same journal

Suppression of Oscillation and Ghosting in RF-Spoiled Gradient-Echo-Based Dynamic Imaging.

Magnetic resonance in medicine·2026
Same journal

A Simple, Dynamic Geometric Phantom for MRI and CT Reconstruction Pipelines: Beyond Shepp-Logan.

Magnetic resonance in medicine·2026
Same journal

7T 3D-EPI PCASL With High SNR Efficiency and Robustness to Through-Plane B<sub>0</sub> Field Gradients.

Magnetic resonance in medicine·2026
Same journal

A Comparison of Tissue Property Values Estimated Using Conventional Cardiac MRF and MT-Cardiac MRF.

Magnetic resonance in medicine·2026
Same journal

Dependence of the Extra-Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter.

Magnetic resonance in medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 10, 2026

MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T
10:22

MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T

Published on: January 16, 2021

5.8K

31P MRSI Coil Combination Using 23Na Sensitivity Information.

Jiying Dai1,2, Mark Gosselink1, Zahra Shams1

  • 1Precision Imaging Group, University Medical Center Utrecht, Utrecht, Utrecht, the Netherlands.

Magnetic Resonance in Medicine
|November 27, 2025
PubMed
Summary
This summary is machine-generated.

This study improves phosphorus-31 magnetic resonance spectroscopic imaging (31P MRSI) by using sodium-23 (23Na) sensitivity maps for optimal channel combination. This method enhances signal-to-noise ratio (SNR) in low-SNR 31P MRSI data compared to traditional approaches.

Keywords:
MRSImulti‐channel coil combinationmulti‐nuclear

More Related Videos

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.7K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

20.0K

Related Experiment Videos

Last Updated: Jan 10, 2026

MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T
10:22

MRM Microcoil Performance Calibration and Usage Demonstrated on Medicago truncatula Roots at 22 T

Published on: January 16, 2021

5.8K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.7K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

20.0K

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Spectroscopy
  • Biophysics

Background:

  • 31P MRSI is crucial for metabolic imaging but suffers from low signal-to-noise ratio (SNR).
  • Optimal combination of multi-channel receiver data is essential for improving 31P MRSI quality.
  • Traditional methods rely on low-SNR 31P data for sensitivity estimation, potentially introducing bias.

Purpose of the Study:

  • To develop and validate a novel method for combining 31P MRSI receive channels.
  • To leverage high-SNR 23Na sensitivity maps for improved 31P MRSI signal combination.
  • To overcome limitations of traditional self-weighting methods in low-SNR 31P MRSI.

Main Methods:

  • Utilized a 15-channel X-nuclei head coil for simultaneous 23Na and 31P imaging.
  • Acquired low-SNR 31P MRSI and high-SNR 23Na sensitivity data.
  • Combined 31P MRSI signals using 23Na sensitivity maps, validated via simulations, Monte Carlo studies, and in vivo experiments.

Main Results:

  • Electromagnetic simulations showed <5% SNR loss with 23Na sensitivities.
  • 23Na-based combination improved SNR in simulated and in vivo 31P spectra.
  • The proposed method avoided the SNR overestimation bias inherent in self-weighting.

Conclusions:

  • 31P MRSI channel combination using 23Na sensitivities offers superior performance.
  • This approach enhances SNR and reduces bias in low-SNR 31P MRSI.
  • The method is effective when using the same receiver array for both nuclei.