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Quality of Life in Chronic Heart Failure With Obstructive Sleep Apnea: A Systematic Review
Francesco Limonti1, Giovanni Cangelosi2, Diaratou Dabre3
1Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Nursing Open
|November 28, 2025
Summary
Obstructive sleep apnea significantly impacts quality of life in chronic heart failure patients. Continuous positive airway pressure shows benefits, but adaptive servo-ventilation requires caution, highlighting the need for personalized care.
Area of Science:
- Cardiology
- Sleep Medicine
- Public Health
Background:
- Chronic heart failure (CHF) and obstructive sleep apnea (OSA) frequently coexist.
- The impact of OSA on quality of life (QoL) in CHF patients is not fully understood.
- Effective management strategies for sleep-disordered breathing (SDB) in CHF are crucial.
Purpose of the Study:
- To describe QoL in patients with CHF and coexisting OSA.
- To evaluate the effects of SDB treatments on QoL, functional capacity, and cardiac outcomes in CHF patients.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Comprehensive literature search across major databases (PubMed, CINAHL, Scopus, Web of Science) up to March 2024.
- Quality assessment using Joanna Briggs Institute Critical Appraisal Checklists.
Main Results:
- Fourteen studies (2048 patients) indicated SDB is linked to reduced QoL, physical capacity, and cardiac function in CHF.
- Continuous positive airway pressure (CPAP) improved respiratory events, sleep quality, left ventricular function, and exercise performance.
- Adaptive servo-ventilation (ASV) reduced central events but increased mortality in reduced ejection fraction patients; nocturnal oxygen therapy had limited QoL benefits; exercise programs improved function and QoL.
Conclusions:
- OSA negatively affects QoL in CHF patients.
- CPAP is beneficial for selected CHF patients with SDB.
- ASV use requires caution; personalized management approaches are essential for optimizing outcomes.
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