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Outcomes following nurse-led day-case paracentesis
Mahir Yousuff1, Pramudi Wijayasiri2, Renee Ma1
1NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University, Nottingham, UK.
Nurse-led therapeutic paracentesis (TP) for refractory ascites is safe and effective. While complications are low, mortality remains high, especially for patients with hepatocellular carcinoma and ongoing alcohol use.
Area of Science:
- Hepatology
- Gastroenterology
- Clinical Nursing
Background:
- Refractory ascites is a common complication of decompensated cirrhosis.
- Therapeutic paracentesis (TP) is a primary intervention for symptom relief.
- Rising demand necessitated innovative service delivery models.
Purpose of the Study:
- To evaluate the safety and efficacy of a nurse-led, day-case therapeutic paracentesis service.
- To assess complication rates and mortality associated with this model of care.
- To identify factors influencing patient survival post-TP.
Main Methods:
- Retrospective analysis of patients with decompensated cirrhosis undergoing nurse-led day-case TP.
- Data collected from January 2017 to December 2021.
- Systematic collection of clinical and outcome data, including complications and survival.
Main Results:
- 2,530 procedures performed on 340 patients.
- Minor complications occurred in 2.1% of cases; 0.9% required hospital admission.
- One-year survival was 61%; 30-day and 90-day mortality rates were 21.0% and 33.1%.
- Independent predictors of 1-year mortality included older age, hepatocellular carcinoma, and ongoing alcohol use.
Conclusions:
- Nurse-led, day-case TP is a safe and effective management strategy for refractory ascites.
- The service successfully manages symptom relief with low complication rates.
- High mortality persists in this patient group, highlighting the need for targeted interventions for those with hepatocellular carcinoma and alcohol use.
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