Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Equity Theory01:26

Equity Theory

238
Equity theory explains how our sense of fairness influences the dynamics of close relationships. Rooted in social psychology, the theory posits that individuals evaluate fairness by comparing the ratio of their contributions to the rewards they receive. Relationship satisfaction is highest when these ratios are perceived as balanced between partners, promoting mutual reciprocity and a sense of justice.Equity vs. Equality in RelationshipsEquity is distinct from equality. Fairness does not...
238
Creative Thinking01:25

Creative Thinking

1.3K
Creative thinking encompasses innovative and unconventional methods for addressing challenges, often leading to groundbreaking solutions. Instead of focusing solely on enhancing existing systems, such as increasing smartphone battery capacity, creative thinking might inspire advancements like energy-efficient batteries or processors that minimize power consumption. This multidimensional approach underscores the importance of exploring novel pathways to innovation.
Divergent thinking is the...
1.3K
Emerging Adulthood01:27

Emerging Adulthood

577
Jeffrey Arnett's concept of emerging adulthood offers a framework to understand the unique developmental stage between adolescence and full-fledged adulthood, generally from ages 18 to 25. This period is marked by extensive exploration and shifts in identity, relationships, and career choices, a process known in psychology as role experimentation. Emerging adulthood reflects the evolving cultural expectations surrounding adulthood and the dynamic process of personal transformation during...
577
Aging01:26

Aging

568
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
568
Current Trends in Nursing I01:28

Current Trends in Nursing I

5.2K
Current trends in nursing include:
5.2K
Growth versus Fixed Mindset01:24

Growth versus Fixed Mindset

215
Carol Dweck introduced the term mindset to describe individuals' beliefs about their intellectual and personal capabilities. These beliefs significantly influence psychological processes such as motivation, goal-setting, and perseverance, ultimately shaping academic and life outcomes. Individuals generally possess one of two mindsets- a fixed or a growth mindset—each promoting different responses to success, failure, and challenge.Fixed vs. Growth MindsetA fixed mindset assumes that one's...
215

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Benjamin Widom (1930-2024) and the "∫" : Physical Chemist, Theorist, and Mentor.

The protein journal·2026
Same author

Genetic modifiers of Friedreich's ataxia pathophysiology in Drosophila melanogaster - A systematic review and meta-analysis.

Free radical biology & medicine·2026
Same author

Molecular Stability as a Translational Gate: A Structured Framework for Target Validation in Genetic Cardiomyopathy.

Cureus·2026
Same author

Recent advances in detection techniques regarding predictive, prognostic, and diagnostic biomarkers in solid cancers and its future challenges.

Advances in cancer research·2026
Same author

Biomarkers for targeted therapy and treatment decision making.

Advances in cancer research·2026
Same author

PFDA Influences the Structure of the Globular Milk Protein, α-Lactalbumin: Implications for Its Ability to Bind a Physiologically Crucial Cofactor.

Chemical research in toxicology·2026
Same journal

Preface.

Progress in brain research·2025
Same journal

Mindfulness and meditation: Promoting emotional and cognitive health.

Progress in brain research·2025
Same journal

Cognitive stimulation enhancing memory and mental function.

Progress in brain research·2025
Same journal

The science behind non-pharmacological interventions.

Progress in brain research·2025
Same journal

Technology-assisted interventions for neuropsychiatric disorders.

Progress in brain research·2025
Same journal

Ethical consideration in non-pharmacological treatments for neuropsychiatric disorders.

Progress in brain research·2025
See all related articles

Related Experiment Video

Updated: Jan 10, 2026

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups
14:14

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

Published on: May 13, 2022

6.3K

Future horizons: Innovation, aging, and equity.

Manoj Kumar Jana1, Vishnu Swarup1, Suryaprakash Tripathy2

  • 1Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Progress in Brain Research
|November 28, 2025
PubMed
Summary
This summary is machine-generated.

Precision medicine offers personalized treatments for neurodegenerative diseases (NDDs) by integrating AI, multi-omics, and biomarkers for early diagnosis and tailored therapies. Overcoming barriers like data standardization and equitable access is crucial for managing NDDs as chronic conditions.

Keywords:
Alzheimer’s diseaseArtificial intelligenceBiomarkersEarly diagnosisGene therapyHealth disparitiesMulti-omics integrationNeurodegenerative diseasesParkinson’s diseasePersonalized treatmentPharmacogenomicsPrecision medicineTranslational research

More Related Videos

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.6K
Using Generative Art to Convey Past and Future Climate Transitions
06:10

Using Generative Art to Convey Past and Future Climate Transitions

Published on: March 31, 2023

1.4K

Related Experiment Videos

Last Updated: Jan 10, 2026

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups
14:14

The Innovation Arena: A Method for Comparing Innovative Problem-Solving Across Groups

Published on: May 13, 2022

6.3K
Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.6K
Using Generative Art to Convey Past and Future Climate Transitions
06:10

Using Generative Art to Convey Past and Future Climate Transitions

Published on: March 31, 2023

1.4K

Area of Science:

  • Neuroscience and Precision Medicine
  • Genomics and Bioinformatics
  • Artificial Intelligence in Healthcare

Background:

  • Neurodegenerative diseases (NDDs) like Alzheimer's and Parkinson's present a growing global health challenge, particularly with aging populations.
  • Conventional treatments are insufficient due to disease heterogeneity, complex molecular pathways, and unpredictable clinical courses.
  • Rising socioeconomic costs necessitate novel, personalized treatment strategies.

Purpose of the Study:

  • To explore the transformative potential of precision medicine in managing neurodegenerative diseases.
  • To highlight advancements in AI, multi-omics, and biomarker research for early diagnosis and personalized treatment.
  • To address challenges and propose solutions for the translation of precision medicine into clinical practice.

Main Methods:

  • Patient stratification using genetic risk profiles, neuroimaging, and fluid biomarkers (e.g., amyloid-beta, tau, alpha-synuclein).
  • Application of artificial intelligence (AI) platforms for disease progression forecasting and treatment tailoring.
  • Integration of pharmacogenomics for individualized drug regimens.
  • Leveraging communal biobanks and AI-enabled big data analysis for drug development and target validation.

Main Results:

  • AI and multi-omics enable patient stratification for early diagnosis and focused interventions.
  • Gene therapy, antisense oligonucleotides (ASOs), and pharmacogenomics offer precise treatment strategies.
  • Innovations like CRISPR-mediated editing and ambient neuroimaging facilitate personalized, early-stage interventions.

Conclusions:

  • Precision medicine represents a paradigm shift, moving NDD management from fatal diagnoses to chronic disease control.
  • Key challenges include biomarker validation, multi-omics standardization, equitable access to diagnostics and therapies, and ethical considerations.
  • Integrated networks, public-private partnerships, and global regulatory harmonization are essential for successful implementation and equitable access.