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Modafinil-Induced Hyperkinetic Movements in Post-Stroke Patients: A Case Series.
Mahendra Javali1, Anish Mehta1, Chandrashekhar Enuguri1
1Department of Neurology, Ramaiah Medical College and Hospitals, Ramaiah University of Applied Sciences, Bengaluru, India.
Modafinil, used for stroke-related sleepiness, may rarely cause involuntary movements in elderly patients. These hyperkinetic movements are reversible upon discontinuing the medication.
Area of Science:
- Neurology
- Pharmacology
Background:
- Modafinil is a wakefulness-promoting agent prescribed off-label for post-stroke hypersomnolence.
- While generally safe, rare central nervous system adverse effects like hyperkinetic movement disorders have been associated with modafinil use.
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