Real-World Case Series on Surgi-ORC® in ENT Surgery

Effective hemostasis is essential in ENT surgical operations to reduce blood loss and improve postoperative recovery. This case series assesses the hemostatic efficacy and safety of Surgi-ORC^® Knit, an absorbable oxidized regenerated cellulose (ORC) hemostat, in four patients undergoing four different ENT operations. This case series included four patients who underwent parotidectomy, thyroidectomy, neck mass excision, and submandibular excision. To control bleeding, a Surgi-ORC^® Knit was applied to the bleeding site. The study's primary objective was to monitor time to hemostasis for bleeding control in ENT surgery. The secondary aim of safety monitoring was to conduct a 60-day follow-up to confirm complete absorption and assess for adverse events. Along with this, the handling characteristics of the product were also assessed. Surgi-ORC^® attained hemostasis within the range of 0.93 to 2.1 minutes. No adverse events were reported, and all patients had stable recoveries. The surgeons found that the product was easy to apply and had good tissue adherence. Surgi-ORC^® was entirely absorbed within 28 days, which was confirmed by radiological imaging. On follow-up day 60, there were no signs of infections, adhesions, granuloma formation, or foreign body reactions. Surgi-ORC^® Knit is a viable treatment option for managing bleeding in ENT surgeries. Surgeons found its user-friendly application, stability, and easy delivery in intricate surgery locations to be noteworthy advantages. Its safety is bolstered by complete absorption and no further complications.