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Long-Term Disease Control With Lenvatinib in Metastatic Malignant Struma Ovarii: A Case Report
Ryota Kawano1, Tomoko Sumikura2, Kohki Shimazu3
1Otolaryngology - Head and Neck Surgery, Osaka General Medical Center, Osaka, JPN.
Malignant struma ovarii, a rare ovarian tumor, can be treated long-term with lenvatinib (LVB) for metastatic disease. This therapy showed potential for sustained tumor control, even with dose adjustments and interruptions.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Medical Oncology
Background:
- Struma ovarii is a rare monodermal teratoma primarily composed of thyroid tissue.
- While typically benign, malignant transformation can occur, presenting with local invasion or metastasis.
- Malignant struma ovarii often mimics poorly differentiated thyroid carcinoma.
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